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Treat with diphoterine and hexafluorine is one of the emergency treatment method for hydrofluoric acid burns. The application of Diphoterine in the treatment of ocular alkali burns was conducted by the Medical Center of the University of Fort-Martinique, Martinique, France. The aim of the study was to compare the effect of washing with saline or Diphoterine in ocular burns in an emergency. A total of 66 patients were included in the study, and the results showed that the number of days of corneal epithelial healing with a saline wash was 11.1 ± 1.4 days in the 1 degree eye burns, and the corneal epithelium was cleaned with Diphoterine Healing days were 1.9 ± 1 days; corneal epithelium healing days were 10 ± 9.2 days in the case of 2-degree eye burns and 5.6 ± 4.9 days in the Diphoterine-treated corneal epithelium day. The conclusion was not reached because of the insufficient use of Diphoterine to clean 3 ° and 4 ° eye burns.

Hexafluorine is used to hydrofluoric acid or hydrofluoric acid and nitric acid mixed burn eye, skin treatment research is the French ValmondoisPREVOR laboratory and other institutions in a German smelter carried out. Prior to the study, the plant trained staff on how to apply (Hexa hexaflurane fluoride) to deal with chemical burns. All burned patients received Hexafluorine emergency flushing treatment within two minutes of the burn (30 to 120 seconds): 500 ml of Hexafluorine was applied to eye burns, and skin burns The flushing process was carried out using a Hexafluorine 5 liter portable injector. When the injured arrived at the factory infirmary, they received the second hexaflurane (Hexafluorine) washing treatment. The results of the study showed that none of the 11 patients who had been treated with Hexafluorine had any type of chemical burn sequelae, nor had any medical or surgical treatment been required, and that no one had delayed work because of injury. 

However, previous literature has shown that a further deterioration of the wound remains unavoidable, even after rinsing with water and subsequent injection of calcium gluconate, after burns of high concentrations of hydrofluoric acid. If the area of skin burned by hydrofluoric acid exceeds the area of the skin Of 2.5%, it is likely to develop into a system of hydrofluoric acid (hypocalcemia, hypomagnesemia and hyperkalemia).